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Evidence-based kidney and metabolic health, free for everyone.

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Plain-English guidance from Sean Hashmi, MD, a board-certified nephrologist and obesity-medicine specialist. Free, with no ads and no sponsorships, because good health information should not sit behind a paywall.

SELF Principle is a registered 501(c)(3) nonprofit. Free, no ads, no sponsorships.

More than 140,000 subscribers and 12 million views on YouTube. Every claim cited. Always free.

The four habits that work like medicine

The SELF Principle is built on four evidence-based pillars.

S

Sleep

Sleep is medicine. Deep sleep is when your body repairs and your blood sugar resets.

E

Exercise

Exercise is medicine. Movement protects your kidneys and helps reverse metabolic disease.

L

Love

Love is medicine. Connection and purpose lower stress and are linked to a longer, healthier life.

F

Food

Food is medicine. What you eat every day is one of the strongest tools you have.

Dr. Sean Hashmi Portrait

Why you can trust this

Sean Hashmi, MD is a board-certified nephrologist and obesity-medicine specialist. Every recommendation is drawn from peer-reviewed research and named clinical guidelines, with no ads and no sponsorships shaping the content.

Latest teaching

Watch anytime, or join Dr. Hashmi live: free monthly AMA, second Thursday, 6 PM Pacific.

KIDNEY

The Kidney Guide

Kidney damage is silent. 9 in 10 adults with early kidney disease do not know they have it.

Three free guides to start

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METABOLIC

The GLP-1 Guide

What nobody tells you about GLP-1s. 25 to 40 percent of the weight you lose on Ozempic, Wegovy, Mounjaro, or Zepbound is muscle.

LONGEVITY

The Longevity Guide

The everyday habits that actually add healthy years.

Evidence-based health in your inbox.

Plain-English science, free every week. No hype, no spam. From the doctor more than 140,000 people follow on YouTube.

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